Ya-Hong Liu

Ya-Hong Liu

 Address: South China Agricultural University, 483 Wushan Road, Guangzhou city 510642, China
E-mail: gale@scau.edu.cn
Telephone: +86-20-85280006

Personal Profile

Dr. Ya-Hong Liu is the Vice President of South China Agricultural University. She is also a Professor in Veterinary pharmacology and toxicology. Her research areas include risk assessment and control of antimicrobial resistance of animal original bacteria, veterinary drug residue detection and ecotoxicology, development and clinical evaluation of new veterinary drugs. She has led more than 50 scientific research projects with research funds totaling more than 50 million RMB. She was also awarded the Changjiang Scholar, the National Science Fund for Distinguished Young Scholars, a second prize of the State Science and Technology Progress Award, and six other provincial and ministerial awards. Having published more than 197 papers in domestic and international journals, such as Nature Microbiology, Antimicrobial Agents and Chemotherapy and The Veterinary Journal, Dr. Liu has also acquired a national class II new veterinary drug certificate and 10 invention patents.

Education/Training 

INSTITUTION AND LOCATIONDEGREEMM/YYFIELD OF STUDY

Northeast Agricultural University, P. R. ChinaB.V. Sc.Sep., 1985-Jul., 1990Agriculture

Northeast Agricultural University, P. R. ChinaM.S.Sep., 1990-Jul., 1993Veterinary pharmacology and toxicology

South China Agricultural University, P. R. ChinaPh.D.Sep., 1993-Jul., 1996Veterinary pharmacology and toxicology

North Carolina State University, USAVisiting scholarJun., 1997-Dec., 1997College of Veterinary Medicine

University of Michigan, USAPostdocFeb., 2000-Feb., 2001College of Pharmacy

Working Experience 

INSTITUTION AND LOCATIONMM/YYPOSITION

College of Veterinary Medicine, South China Agricultural University, P. R. ChinaJul., 1996-Nov., 1998Teacher

College of Veterinary Medicine, South China Agricultural University, P. R. ChinaDec., 1998-Nov., 2003Associate Professor/Master tutor

College of Veterinary Medicine, South China Agricultural University, P. R. ChinaDec., 2003Professor/Doctoral supervisor

Quality Supervision and Inspection Center of animal products, the Ministry of agriculture, P. R. ChinaMay, 2001-Dec., 2006

Jan., 2007-Dec., 2008Vice director

College of Veterinary Medicine, South China Agricultural University, P. R. ChinaJan., 2007-Dec., 2008Assistant Dean

College of Veterinary Medicine, South China Agricultural University, P. R. ChinaJan., 2009-Jun., 2015Dean

South China Agricultural University, P. R. ChinaJun., 2016-NowVice President

Grants in Scientific Research Projects

National Natural Science Foundation of China: Transmission Mechanism and Source of Carbapenem-Resistant gene, 31730097, 2018-2022

State's Key Project of Research and Plan Development: Significant pathogens resistance test and control technology in livestock and poultry, 2016YFD0501300, 2016-2020 

Projects of International Cooperation and Exchanges NSFC : Mechanism of Salmonella adaptation assisted by resistance plasmids under different selective pressure, 30520103918,2016-2020

National Natural Science Fund for Distinguished Young Scholars: Veterinary pharmacology and toxicology, 31125026, 2011-2015

The Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China: Safety assessment of veterinary antimicrobials, IRT13063, 2014-2017

United Fund of National Natural Science and Guangdong Province: The influence of antimicrobials residues on the development and dissemination of antimicrobial resistance of pathogenic organism, U1201214, 2014-2017

Public Benefit Project of Industry research: The dissemination of antimicrobial resistance in pathogenic organism, 201203040, 2012-2016

The Natural Science Foundation of Guangdong Province: Prevention and mechanism of significant pathogens in poultry and livestock, S2012030006590, 2014-2018

Science and Technology Planning Project of Guangdong Province: Enteric-coated microcapsule preparation of new veterinary antibiotics, 2012A020800004, 2012-2016

Selected Peer-Reviewed Publications (from more than 197 papers)

Zhou, Y.F.; Xiong, Y.Q.; Tao, M.T.; Li, L.; Bu, M.X.; Sun, J.; Liao,X.P.;Liu,Y.H. *,Increased activity of linezolid in combination with rifampicin in a murine pneumonia model due to MRSA. The Journal of antimicrobial chemotherapy. 2018.

Fang, L.X.; Li ,X.P.; Deng, G.H.; Li, S.M.; Yang, R.S.; Wu, Z.W.; Liao,X.P.;Sun,J.;Liu,Y.H. *, High Genetic Plasticity in Multidrug-Resistant Sequence Type 3-IncHI2 Plasmids Revealed by Sequence Comparison and Phylogenetic Analysis. Antimicrobial agents and chemotherapy. 2018,62.

Sun ,J.; Zeng ,X.; Li, X.P.; Liao, X.P.; Liu ,Y.H. *; Lin, J. *, Plasmid-mediated colistin resistance in animals: current status and future directions. Animal health research reviews. 2017,18,136-52.

Sun, J. ;Zhang ,H.;Liu ,Y.H. *; Feng ,Y.*,Towards Understanding MCR-like Colistin Resistance. Trends in microbiology. 2018,26,794-808.

Zhou, Y. F.; Tao, M. T.; Huo, W.; Liao, X. P.; Sun, J.; Liu, Y. H. *, In Vivo Pharmacokinetic and Pharmacodynamic Profiles of Antofloxacin against Klebsiella pneumoniae in a Neutropenic Murine Lung Infection Model. Antimicrob Agents Chemother 2017, 61.

Zhou, Y. F.; Tao, M. T.; He, Y. Z.; Sun, J.; Liu, Y. H.; Liao, X. P. *, In Vivo Bioluminescent Monitoring of Therapeutic Efficacy and Pharmacodynamic Target Assessment of Antofloxacin against Escherichia coli in a Neutropenic Murine Thigh Infection Model. Antimicrob Agents Chemother 2017.

Zhou, Y. F.; Tao, M. T.; Feng, Y.; Yang, R. S.; Liao, X. P.; Liu, Y. H.; Sun, J.*, Increased activity of colistin in combination with amikacin against Escherichia coli co-producing NDM-5 and MCR-1. J Antimicrob Chemother 2017, 72, 1723-1730.

Jian Sun, Run-Shi Yang, Qijing Zhang, Youjun Feng, Liang-Xing Fang, Jing Xia, Liang Li, Xiao-Yue Lv, Jia-Hong Duan, Xiao-Ping Liao* and Ya-Hong Liu*. Co-transfer of blaNDM-5 and mcr-1 by an IncX3-X4 hybrid plasmid in Escherichia coli. Nature Microbiology.26;1:16176,2016 Sep.

Chen Y, Sun J, Liao XP, Shao Y, Li L, Fang LX, Liu YH*. Impact of enrofloxacin and florfenicol therapy on the spread of OqxAB gene and intestinal microbiota in chickens. Vet Microbiol.30;192:1-9,2016 Aug. 

Sun, J.; Xu, Y.; Gao, R.; Lin, J.; Wei, W.; Srinivas, S.; Li, D.; Yang, R. S.; Li, X. P.; Liao, X. P.; Liu, Y. H. *; Feng, Y. *, Deciphering MCR-2 Colistin Resistance. mBio 2017, 8.

Yang RS, Feng Y, Lv XY, Duan JH, Chen J, Fang LX, Xia J, Liao XP, Sun J, Liu YH*. Emergence of NDM-5 and MCR-1-Producing Escherichia coli Clone ST648 and ST156 from A Single Muscovy Duck. Antimicrob Agents Chemother. pii: AAC.01365-16,2016 Aug 22.

Sun J, Li XP, Yang RS, Fang LX, Huo W, Li SM, Jiang P, Liao XP, Liu YH*. Complete Nucleotide Sequence of IncI2 Plasmid Co-harboring blaCTX-M-55 and mcr-1. Antimicrob Agents Chemother.22;60(8):5014-7,2016 Jul.

Yang QE, Walsh TR, Liu BT, Zou MT, Deng H, Fang LX, Liao XP, Sun J, Liu YH*. Complete Sequence of the FII Plasmid p42-2, Carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli. Antimicrob Agents Chemother.2016 Jun 20;60(7):4336-8.

Yu Y, Zhou YF, Li X, Chen MR, Qiao GL, Sun J, Liao XP, Liu YH*. Dose Assessment of Cefquinome by Pharmacokinetic/Pharmacodynamic Modeling in Mouse Model of Staphylococcus aureus Mastitis. Frontiers in microbiology. 7; 7:1595,2016 Oct.

Guo CN, Liao XP, Wang MR, Wang F, Yan CQ, Xiao X, Sun J, Liu YH*. In vivo Pharmacodynamics of Cefquinome in a neutropenic mouse thigh model of Streptococcus suis serotype 2 at varied initial inoculum sizes. Antimicrob Agents Chemother.14;60(2):1114-20,2015 Dec. 

Sun J, Deng H, Li L, Chen MY, Fang LX, Yang QE, Liu YH*, Liao XP*. Complete nucleotide sequence of cfr-carrying IncX4 plasmid pSD11 from Escherichia coli. Antimicrob Agents Chemother 59:738-741, 2015

Xiao X, Sun J, Yang T, Fang X, Wu D, Xiong YQ, Cheng J, Chen Y, Shi W, Liu YH*. In vivo pharmacokinetic/pharmacodynamic profiles of valnemulin in an experimental intratracheal Mycoplasma gallisepticum infection model. Antimicrob Agents Chemother 59:3754-3760, 2015.

Fang LX, Sun J, Li L, Deng H, Huang T, Yang QE, Li X, Chen MY, Liao XP, Liu YH*. Dissemination of the chromosomally encoded CMY-2 cephalosporinase gene in Escherichia coli isolated from animals. Int J Antimicrob Agents 46:209-213, 2015 

Zhao DH, Zhou YF, Yu Y, Shi W, Yang X, Xiao X, Deng H, Qiao GG, Fang BH, Liu YH*. Integration of pharmacokinetic and pharmacodynamic indices of valnemulin in broiler chickens after a single intravenous and intramuscular administration. Vet J 201:109-115, 2014.

Li L, Liao XP, Liu ZZ, Huang T, Li X, Sun J, Liu BT, Zhang Q, Liu YH*. Co-spread of oqxAB and blaCTX-M-9G in non-Typhi Salmonella enterica isolates mediated by ST2-IncHI2 plasmids. Int J Antimicrob Agents 44:263-268, 2014.

Chen X, He L, Li Y, Zeng Z, Deng Y, Liu YH*, Liu JH*. Complete sequence of a F2: A-: B- plasmid pHN3A11 carrying rmtB and qepA, and its dissemination in China. Vet Microbiol 174:267-271, 2014.

Li L, Liao X, Yang Y, Sun J, Li L, Liu B, Yang S, Ma J, Li X, Zhang Q, Liu YH*. Spread of oqxAB in Salmonella enterica serotype Typhimurium predominantly by IncHI2 plasmids. J Antimicrob Chemother 68:2263-2268, 2013.

Yang SS, Sun J, Liao XP, Liu BT, Li LL, Li L, Fang LX, Huang T, Liu YH*. Co-location of the erm(T) gene and blaROB-1 gene on a small plasmid in Haemophilus parasuis of pig origin. J Antimicrob Chemother 68:1930-1932, 2013. 

Liu BT, Wang XM, Liao XP, Sun J, Zhu HQ, Chen XY, Liu YH*. Plasmid-mediated quinolone resistance determinants oqxAB and aac(6')-Ib-cr and extended-spectrum beta-lactamase gene blaCTX-M-24 co-located on the same plasmid in one Escherichia coli strain from China. J Antimicrob Chemother 66:1638-1639, 2011.

Yue L, Jiang HX, Liao XP, Liu JH, Li SJ, Chen XY, Chen CX, Lu DH, Liu YH*. Prevalence of plasmid-mediated quinolone resistance qnr genes in poultry and swine clinical isolates of Escherichia coli. Vet Microbiol 132:414-420, 2008.

To Students

Confidence is always the primary factor of being great.


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